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November 1976

Postradiation Motor Neuron Syndrome

Author Affiliations

From the Sections of Neurology and Neurosurgery, Dartmouth-Hitchcok Medical Center, Hanover, NH. Dr Sadowsky is now with the US Air Force Hospital, Wiesbaden, West Germany.

Arch Neurol. 1976;33(11):786-787. doi:10.1001/archneur.1976.00500110054010

• We report an unusual case of selective lower motor neuron syndrome (MNS) complicating whole neuraxis radiation therapy. Only three well-documented similar cases have been found in a thorough review of the literature. The syndrome has a stereotyped time course and is selflimited. We discuss here possible pathogenetic mechanisms and their relationship to motor neuron disease.

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