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February 1977

Neurologic Aspects of Hereditary Hemorrhagic Telangiectasia: Report of Two Cases

Author Affiliations

From the Department of Neurology, University of Iowa Hospitals and Clinics, Iowa City.

Arch Neurol. 1977;34(2):101-104. doi:10.1001/archneur.1977.00500140055011

• The several neurologic manifestations of hereditary hemorrhagic telangiectasia (HHT) may be caused by complications of pulmonary arteriovenous fistulae or associated central nervous system vascular malformations. The presence of skin and mucosal telangiectases should alert the clinician to the possibility of the disorder and in turn of its potential for associated neurologic disease, including cerebral hemorrhage and abscess. This report describes two cases and demonstrates that the clinical spectrum of HHT should be enlarged to include its admittedly rare, but serious, neurologic aspects.