• We describe a case of central anticholinergic syndrome with choreiform movements after an overdose of pheniramine aminosalicylate. The symptoms and signs of the condition were reversed by the intravenous administration of the cholinesterase-inhibitor tetrahydroaminacrine. We also discuss the concept of adrenergic-cholinergic imbalance in relation to this case and recommend the use of centrally acting anticholinesterase agents in the treatment of specific cases of drug overdose.
Mendelson G. Pheniramine Aminosalicylate Overdosage: Reversal of Delirium and Choreiform Movements With Tacrine Treatment. Arch Neurol. 1977;34(5):313. doi:10.1001/archneur.1977.00500170067014
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