To the Editor.—
The article entitled "Neurologic Aspects of Hereditary Hemorrhagic Telangiectasia" in the February issue of the Archives (34:101, 1977) prompts me to make the following comment.Approximately two years after the publication of my article1 on the same subject (quoted in the above article), I had the opportunity to study the mother of the patient I described as having hereditary hemorrhagic telangiectasia with both pulmonary and cerebral arteriovenous malformations. The mother had already been strongly suspected of also having a pulmonary arteriovenous malformation at the time of my writing; she was admitted to hospital with a sudden severe headache and brief loss of consciousness. Investigations verified that, like her daughter, she too had asymptomatic pulmonary and symptomatic cerebral arteriovenous malformations.To my knowledge, this is the first family with hereditary hemorrhagic telangiectasia in which members of two consecutive generations have coexistent pulmonary as well as cerebral arteriovenous malformations.