[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.204.52.4. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
May 1977

EEG Correlations With Biochemical Abnormalities in Reye's Syndrome

Arch Neurol. 1977;34(5):321. doi:10.1001/archneur.1977.00500170075020
Abstract

To the Editor.—  The recent article by Trauner et al (Arch Neurol 34:116, 1977) on EEG correlation with serum short-chain fatty acids in Reye's syndrome raised a possibility that the severity of the encephalopathy and associated EEG abnormalities in Reye's syndrome may be partly the result of organic acid effects on the CNS. They concluded the article by encouraging other investigators to continuously monitor EEG in a series of patients with Reye's syndrome in order to fully study the effects of biochemical abnormalities on the EEG pattern. In view of the evidence for increased intracranial pressure secondary to cerebral edema being the major contributing factor to death in Reye's syndrome1,2 and the improvement both clinically and on EEG with control of the pressure,3 the question is raised whether the improvement in EEG mentioned in the article by Trauner et al was a reflexion of the change in short-chain

×