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October 1977

Reversible Corticospinal Tract Disease Due to Hyperthyroidism

Arch Neurol. 1977;34(10):647-648. doi:10.1001/archneur.1977.00500220081018

• Corticospinal tract malfunction was seen in a patient with Graves' disease. The absence of intracranial and intraspinal lesions likely to cause the neurologic manifestations and their regression after control of thyroid dysfunction favors a cause-effect relationship. We review and compare similar cases previously reported and discuss the mechanisms.