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October 1977

Acute Neurological Forms of Infectious Mononucleosis

Author Affiliations

Institut de Médecine—Neurologie Hôpital Universitaire de Bavière B-4020 Liege, Belgium

Arch Neurol. 1977;34(10):651. doi:10.1001/archneur.1977.00500220085024

To the Editor.—  We recently reported three unusual neurological complications of infectious mononucleosis (IM).1 One case was almost identical to the one published by Friedland and Yahr in the March issue of the Archives (34:186, 1977.)

Report of a Case.—  Our patient, an 18-year-old man, abruptly had a grand mal seizure. For the next two days, he remained comatose, with meningeal signs and bilateral Babinski signs, and showed incessant choreoathetotic movements of the four limbs, face, and trunk. He suffered again from two generalized seizures the day after his admission. There was no classical sign of IM and CSF was normal. The EEG pattern was strongly disturbed. There were 17% atypical lymphocytes in the blood and the heterophile titer was to 1:224 on the fifth day of illness. Without any specific treatment, the patient completely recovered in a week.

Comment.—  Such an acute neurological syndrome with seizures and involuntary

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