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November 1977

Petit Mal Epilepsy: A Search for the Precursors of Wave-Spike Activity

Arch Neurol. 1977;34(11):726. doi:10.1001/archneur.1977.00500230096035

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As indicated by the title, the book presents a critical review of experimental animal studies of one of the most fundamental paroxysmal EEG discharges, the bilaterally synchronous, 3/sec spike and wave of petit mal. Additionally, the applicability of this research to clinical neurology is stressed. Most experimental data of the author and the ideas expressed in this book were previously published only in Russian and are, therefore, in a sense new to the English literature. The content of the book spans from experimental findings in research on animal models to applicability of these findings to clinical problems. Included are such diverse subjects as learning and reinforcement, asymmetry of the brain hemispheres, the nature of evoked potentials, and the effect of x-irradiation on the embryo.

The main theme, however, is the author's conviction that wave-spike discharges of petit mal epilepsy and related forms of abnormal activity develop from normal precursors.

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