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February 1978

Clinical Syndromes of Myasthenia in Infancy and Childhood: A Review

Author Affiliations

From the Departments of Neurology and Pediatrics, Vanderbilt University Medical Center, Nashville, Tenn.

Arch Neurol. 1978;35(2):97-103. doi:10.1001/archneur.1978.00500260035009

• Ten clinical syndromes of defective neuromuscular transmission in infancy and childhood are reviewed. Autoimmune, genetic, infectious, and pharmacologic mechanisms have been implicated. These disorders manifest themselves in a variety of ways including severe respiratory insufficiency. Prompt diagnosis and treatment may be lifesaving.

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