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February 1979

Intractable Sneezing: Case Report and Literature Review

Author Affiliations

From the Department of Neurology, University of New Mexico School of Medicine, and the Veterans Administration Hospital, Albuquerque.

Arch Neurol. 1979;36(2):111-112. doi:10.1001/archneur.1979.00500380081012

• Intractable sneezing is rare; the 12th case is reported here. Various causative factors have been identified in the literature; these include psychologic problems, cervical lymphadenitis, epilepsy, and allergy. The sneeze reflex consists of two phases, nasal and respiratory, which are mediated by cranial nerves V and VII and by brain-stem respiratory centers. Hypotheses that have been proposed to explain the multiple causation of sneezing are the concept of the trigeminal system as a central neuronal pool, optic-trigeminal summation, and parasympathetic generalization.

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