• In ten monkeys, selective segmental lesions of the dorsal columns at the upper thoracic and middle cervical levels resulted in almost total attenuation of the cortical evoked potential responses to peripheral nerve stimulation. Conversely isolated segmental dorsal column preservation showed intact transmission of the evoked responses at rostral spinal cord, nucleus ventralis posterior lateralis, and cortical levels. Responses recorded from the intralaminar thalamic nuclei in the region of nucleus centrum medianum were unaffected by dorsal column ablation, but were markedly attenuated following bilateral ventral column ablation.
Cusick JF, Myklebust JB, Larson SJ, Sances A. Spinal Cord Evaluation by Cortical Evoked Responses. Arch Neurol. 1979;36(3):140–143. doi:10.1001/archneur.1979.00500390058005
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.