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March 1979

Visual Evoked Responses in Pernicious Anemia

Author Affiliations

From the Departments of Neurology, Hahnemann Medical College and Hospital of Philadelphia and Wills Eye Hospital, Philadelphia.

Arch Neurol. 1979;36(3):168-169. doi:10.1001/archneur.1979.00500390086010

• We describe three newly diagnosed and untreated cases of pernicious anemia (PA) with clinical features suggestive of subacute combined degeneration. Visual evoked responses (VERs) were evaluated in all three patients. In each instance, delayed responses were obtained, suggesting that involvement of the visual pathways may be an early and perhaps not uncommon manifestation in PA, even in the absence of clinical stigmata of visual impairment. The need for excluding PA in cases of myelopathy with impaired VERs is stressed.