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April 1979

Febrile Seizures in Children-Reply

Arch Neurol. 1979;36(4):254. doi:10.1001/archneur.1979.00500400108028

In Reply.—  Our recent study investigated the effect of febrile seizures on intelligence in children in whom afebrile seizures did not develop subsequently—that is, 97% of children with febrile seizures—and found there to be no impairment. This result is not challenged by Drs Aicardi and Chevrie.With respect to the 3% of the children in whom afebrile seizures did develop after febrile, we agree with Drs Aicardi and Chevrie that they demonstrated an increased frequency of mental impairment.1,2 However, contrary to the statement by Chevrie and Aicardi, it is possible to know beforehand which infants with febrile convulsions are at substantially heightened risk for later afebrile seizures. A small subset of children with febrile seizures (6%)2 can be identified who have a high risk of epilepsy and potentially of associated intellectual deficit.The small subgroup of children with febrile seizures who are at relatively high risk of afebrile seizures