• The appearance of tremors in patients with childhood, chronic spinal muscular atrophy has been known for years. We were struck by the presence of a "muscle tremor" artifact in the ECGs of all our patients with this diagnosis. This observation has not been noted previously. The consistency of this finding in patients with this disease is the basis for this report.
Russman BS, Fredericks EJ. Use of the ECG in the Diagnosis of Childhood Spinal Muscular Atrophy. Arch Neurol. 1979;36(5):317–318. doi:10.1001/archneur.1979.00500410095017
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: