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May 1979

Chemotherapy of Herpes Simplex Virus Infections

Author Affiliations

Department of Pediatrics University of Iowa Hospitals Iowa City, IA 52240

Arch Neurol. 1979;36(5):325. doi:10.1001/archneur.1979.00500410103032

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With the clarification of the spectrum of herpes simplex infections in man and the improvement in diagnostic measures for herpes simplex encephalitis, greater attention is now being given to specific antiviral drug therapy for these conditions.

This soft-covered volume includes 17 papers, in a total of 137 pages, that describe accurately and succintly the current state of knowledge of the various pharmacologic agents available for treatment of herpes simplex infections. Two contributions are primarily of clinical interest, one of which surveys the various forms of human infection with this virus and the second of which describes treatment of herpes simplex encephalitis. The clinical manifestations of the different types of herpes infections are nicely summarized in brief fashion by MacCallum and Patteson. The 13 illustrations in this chapter are of excellent quality and are representative of the discussion. The short paper on treatment of herpes encephalitis reviews the drugs used in

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