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September 1979

'Agenesis' of the Temporal Lobe: A Case Report With Autopsy Findings

Author Affiliations

From the Department of Neurology and Pathology, Pennsylvania Hospital, Philadelphia, and the Neuro-Ophthalmology Unit, Wills Eye Hospital, Philadelphia (Dr Kansu). Dr Zacks is now with the Department of Laboratory Medicine, The Miriam Hospital, Providence.

Arch Neurol. 1979;36(9):590-591. doi:10.1001/archneur.1979.00500450084020

• The temporal lobe agenesis syndrome is a rare congenital abnormality. In previous case reports, this syndrome has been described in association with arachnoid cysts or abnormal collections of CSF. An autopsy performed in the case of our 25-year-old patient revealed agenesis of frontal and temporal lobes without an anatomic cyst. During life the patient had no neurologic abnormalities that could be related to the lesion.