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November 1979

Trial of Baclofen in Amyotrophic Lateral Sclerosis

Arch Neurol. 1979;36(11):715-716. doi:10.1001/archneur.1979.00500470085019

• A trial of the antispastic drug baclofen was made in amyotrophic lateral sclerosis. Some patients noted reduction of tonus and spasticity; but others had no benefit, nor was the course of the disease altered by long-term administration of baclofen. No major side effects occurred.