• Five family members in three successive generations experienced convulsions as newborns. One died during a cyanotic spell. The remaining four are developmentally and neurologically normal, although three continue to have seizure disorders as adults. No underlying inborn error of metabolism has been identified. This family appears to have a familial epilepsy beginning at birth that is transmitted as an autosomal dominant trait.
Pettit RE, Fenichel GM. Benign Familial Neonatal Seizures. Arch Neurol. 1980;37(1):47–48. doi:10.1001/archneur.1980.00500500077012
Artificial Intelligence Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.