• Young normal subjects received 16 g of choline chloride in a double-blind A-B-A design. Short- and long-term memory function was evaluated. Comparison of group means indicated that choline chloride did not significantly affect shortterm memory or long-term memory. However, individual subjects may have had some aspects of long-term memory affected by choline chloride treatments. The results suggest that the effect of lower doses of choline on long-term memory should be evaluated.
Davis KL, Mohs RC, Tinklenberg JR, Hollister LE, Pfefferbaum A, Kopell BS. Cholinomimetics and Memory: The Effect of Choline Chloride. Arch Neurol. 1980;37(1):49–52. doi:10.1001/archneur.1980.00500500079013
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