• Nocturnal myoclonus has been identified as a cause of disturbed sleep and excessive daytime fatigue. To our knowledge, no therapy has heretofore been available to adequately control this problem. We identified this problem clinically in two patients; in one, the phenomenon was observed with a polygraphic sleep recording. Small doses of clonazepam, 1 mg, before retiring were found to specifically control the myoclonus and allow sleep patterns to return to normal.
Oshtory MA, Vijayan N. Clonazepam Treatment of Insomnia due to Sleep Myoclonus. Arch Neurol. 1980;37(2):119–120. doi:10.1001/archneur.1980.00500510077019
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