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March 1980

Treatment With Tryptophan of Levodopa-Associated Psychiatric Disturbances

Arch Neurol. 1980;37(3):155-156. doi:10.1001/archneur.1980.00500520053008

• The effect of 2 to 6 g of tryptophan per day on levodopa-induced psychiatric symptoms was tested in nine patients with Parkinson's disease in a double-blind, placebo-controlled trial. The psychiatric disturbances were not greatly altered by administration of tryptophan.