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March 1980

Treatment With Tryptophan of Levodopa-Associated Psychiatric Disturbances

Author Affiliations

From the Department of Neurology, US Public Health Service Hospital, Staten Island, NY (Drs Beasley and Davenport), the Department of Neurology, University of Oregon Health Science Center, Portland, Ore (Dr Nutt), and the Department of Neurology, National Institutes of Health, Bethesda, Md (Dr Chase).

Arch Neurol. 1980;37(3):155-156. doi:10.1001/archneur.1980.00500520053008

• The effect of 2 to 6 g of tryptophan per day on levodopa-induced psychiatric symptoms was tested in nine patients with Parkinson's disease in a double-blind, placebo-controlled trial. The psychiatric disturbances were not greatly altered by administration of tryptophan.

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