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March 1980

Stiff-Man Syndrome With Abnormalities in CSF and Computerized Tomography FindingsReport of a Case

Arch Neurol. 1980;37(3):182-183. doi:10.1001/archneur.1980.00500520080018

• We report a case of stiff-man syndrome with abnormal spinal fluid. Serum protein values were normal, but the spinal fluid levels of immunogammaglobulin G and acute-phase proteins were elevated. We discuss the possibility of an inflammatory process of the nervous system as a cause for these findings. Another interesting observation in our patient was that of local atrophies seen on computerized tomography, indicating hemispheral and especially brainstem lesions. Furthermore, as a new therapeutic possibility, we demonstrated the improvement of spasms and rigidity under the influence of heat.