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March 1980

Multiple Sclerosis and Serial Computerized Tomography: Delayed Contrast Enhancement of Acute and Early Lesions

Author Affiliations

From the Division of Neurology, Department of Neurology and Neurological Surgery (Drs Morariu and Wilkins) and the Department of Radiology (Dr Patel), Henry Ford Hospital, Detroit.

Arch Neurol. 1980;37(3):189-190. doi:10.1001/archneur.1980.00500520087022

• By demonstrating periventricular contrast-enhanced lesions cranial computerized tomography (CT) supported the diagnosis of multiple sclerosis in a patient with recurrent transient hemiparesis. These abnormalities were present only on delayed films taken one hour after contrast injection and probably represented acute and early demyelinating plaques. Areas of contrast enhancement evolved to isodensity with and without corticosteroid treatment. Brain scan findings mirrored cranial CT abnormalities, and both could be correlated with the clinical status and the course of the disease.

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