Hypoglycorrhachia has been previously reported in mumps meningoencephalitis1 and lymphocytic choriomeningitis.2 The occurrence of significant hypoglycorrhachia in herpes simplex type 2 meningitis has not been previously reported,3 although Craig and Nahmias4 described one patient with a CSF glucose level of 41 mg/dL with a concomitant serum glucose level of 75 mg/dL. I report a case of aseptic meningitis associated with clinical and serologic evidence of a herpes simplex type 2 infection with associated hypoglycorrhachia.
REPORT OF A CASE
A previously healthy 28-year-old woman reported to her gynecologist on Oct 28, 1978, with a four-day history of increasing vulvar discomfort and tenderness in the left inguinal region. A 0.2-cm, tender inguinal lymph node on the left and a small superficial ulcer on the left labia were noted. This was considered typical herpes progenitalis. The patient soon experienced bitemporal throbbing headaches, lower lumbar soreness, diffuse myalgia, nausea, vomiting
Brenton DW. Hypoglycorrhachia in Herpes Simplex Type 2 Meningitis. Arch Neurol. 1980;37(5):317. doi:10.1001/archneur.1980.00500540095019
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