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May 1980

Fatal Mycoplasma pneumoniae Encephalitis in an Adult

Author Affiliations

From the Department of Medicine, University of Maryland School of Medicine and the Maryland Institute for Emergency Medical Services, Baltimore.

Arch Neurol. 1980;37(5):321. doi:10.1001/archneur.1980.00500540099024

Mycoplasma pneumoniae is a rare cause of encephalitis, and adult fatalities have yet to be reported. We report a fatal case of presumed Mycoplasma encephalitis with a description of associated pathologic features.

REPORT OF A CASE  A 29-year-old man previously in excellent health was admitted to University Hospital, Baltimore, with a five-day history of frontal headaches, fever, photophobia, and confusion. The patient was well developed, with a temperature of 38.3 °C. Results of general physical examination were unremarkable, and neurologic examination revealed agitation, disorientation, but no focal findings.Lumbar puncture was traumatic; cell count showed 26 lymphocytes, three leukocytes, and 730 RBCs; the protein level was 58 mg/dL; glucose level was 64 mg/dL, with a serum value of 95 mg/dL. Gram's stain, acid fast, India ink, VDRL test for syphilis, and cultures were negative. Blood cell count included a hemoglobin value of 14.1 g/dL; WBC count of 7,100/cu mm, with

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