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June 1980

The Not-So-Benign Miller Fisher Syndrome: A Variant of the Guillain-Barré Syndrome

Author Affiliations

From the Departments of Neurology (Drs Blau, Casson, and Lieberman) and Clinical Medicine (Dr Weiss), New York University School of Medicine.

Arch Neurol. 1980;37(6):384-385. doi:10.1001/archneur.1980.00500550086016

• Two patients with Fisher's syndrome of ophthalmoplegia, ataxia, and areflexia experienced severe weakness and respiratory distress. Both patients required tracheostomy and assisted ventilation, but both made a complete recovery. Fisher's syndrome is generally considered to be a benign variant of acute infectious polyneuropathy (the Guillain-Barré syndrome). Our two patients demonstrate that the condition is not always benign.

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