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July 1980

Perinatal Neuropathy as an Early Manifestation of Krabbe's Disease

Author Affiliations

From the Departments of Physical Medicine and Rehabilitation (Drs Lieberman and Taylor) and Neurology (Drs Lieberman, Oshtory, and Dreyfus), University of California, Davis, Sacramento Medical Center.

Arch Neurol. 1980;37(7):446-447. doi:10.1001/archneur.1980.00500560076012

• An asymptomatic child with antenatally diagnosed globoid cell leukodystrophy was found to have electrodiagnostic evidence of peripheral neuropathy at 7 weeks of age. The earliest prior such evidence in the literature was in a 6-month-old child. Thus, peripheral neuropathy can be both the initial manifestation and a very early finding in Krabbe's disease.

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