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July 1980

Neuroleptic Malignant Syndrome

Arch Neurol. 1980;37(7):462-463. doi:10.1001/archneur.1980.00500560092019

• The neuroleptic malignant syndrome is an uncommon, severe illness that consists of fever, muscular rigidity, and stupor. Various neuroleptics have been associated with the disease. A detailed neurological, medical, and neuropathological evaluation of this case was performed. Presumably, the syndrome is secondary to biochemical dysfunction of the basal ganglia and possibly of the hypothalmus.