Eosinophilic Meningitis After Repeated lophendylate Injection Myelography

To the Editor.—  Eosinophilic meningitis is rare. It occurs essentially in helminthic infections of the nervous system, and occasionally in fungal and bacterial infections, in lymphoproliferative disorders, and after introduction of foreign material into the CNS.¹ I studied a patient with eosinophilic meningitis after repeated myelography with iophendylate injection (Pantopaque) that responded to therapy with corticosteroids.

Report of a Case.—  A 27-year-old man appeared on Aug 14, 1978, with the complaint of severe neck, occipital, and lower back pain after myelography done on Aug 3, 1978, for chronic lower back pain since 1976. He had had a iophendylate myelogram performed previously, on Oct 29, 1976. At the time of admission, he looked ill, with marked photophobia and diaphoresis. Results of neurological examination were normal except for nuchal stiffness.Roentgenograms of skull, chest, lumbosacral spine, and brain scan and EEG were normal. Sedimentation rate on three occasions was slightly