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October 1980

Use of Adrenal Biopsy in Diagnosing Adrenoleukomyeloneuropathy

Author Affiliations

From the Department of Neurology (Drs Weiss and O'Neill), Division of Endocrinology, Metabolism and Internal Medicine (Dr Nelson), Department of Surgical Pathology (Dr Carney) and Department of Surgery (Dr Edis), Mayo Clinic and Mayo Foundation, Rochester, Minn.

Arch Neurol. 1980;37(10):634-636. doi:10.1001/archneur.1980.00500590058009

• A 22-year-old man was seen with Addison's disease, psychosis, and neurologic abnormalities. A tentative diagnosis of adrenoleukomyeloneuropathy was made. Because of his age, negative family history, and the potentially serious prognosis of this disorder, the diagnosis was verified with an adrenal biopsy. We believe this procedure is the method of choice in confirming the sporadic, atypical case of adrenoleukomyeloneuropathy.

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