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December 1980

Cylindroma Causing Garcin's Syndrome

Author Affiliations

Division of Neurology Duke University Medical Center PO Box 2905 Durham, NC 27710

Arch Neurol. 1980;37(12):786. doi:10.1001/archneur.1980.00500610066014

To the Editor.—  Garcin1 described the now well-known syndrome of paralysis of cranial nerves, often unilateral, due to a malignant tumor invading the base of the skull. The origin of the tumor, usually a sarcoma or fibrosarcoma in the upper nasopharynx, was emphasized years ago.2 We report a case that was due to a cylindroma (adenocystic carcinoma).

Report of a Case.—  A 62-year-old woman was seen in December 1976 for blurred vision. Results of examination were normal. In February 1977, numbness on the right side of her face and tongue developed. In April, her right ear felt plugged, with discomfort and muffled hearing. An otolaryngologist found no cause for the complaints and no abnormality in the nasopharynx. In July, dizziness, nausea, and difficulty in swallowing occurred.There was complete ophthalmoplegia with ptosis on the right, the pupils 3 mm OD, 4 mm OS. The right corneal reflex was

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