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January 1981

Treatment of Status Epilepticus

Author Affiliations

Department of Neurology University of Iowa Hospitals and Clinics Iowa City, IA 52242

Arch Neurol. 1981;38(1):71. doi:10.1001/archneur.1981.00510010097036

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The author has written his views with regard to drug therapy for status epilepticus and supported them with more than 300 references that deal with experimental and clinical reports. General measures of treatment receive attention, but the "primary emphasis is directed in considerable detail at the use of antiepileptic drugs. These are discussed on the basis of current insights, with regard to their indications, actions, dosage, methods of administration, and side effects. Advantages and disadvantages are considered for each drug. Several of the medications that are discussed are not available in the United States. The benzodiazepine lorazepam receives only brief mention, as this monograph was published in 1979.

Therapy is outlined in relation to the categories of generalized convulsive, generalized nonconvulsive, unilateral, and partial status epilepticus. Discussion of eclamptic status and the prophylaxis of status epilepticus is included. Special cautions are given with regard to drug therapy in relation to

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