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To the Editor.—
The letter from Dr. Phillip M. Green (Archives 1980;37:676) was very instructive. Dr Takamiya and I discussed, in our article, the resemblance of presenile dementia to Creutzfeldt-Jakob disease. We could not differentiate these cases completely from Creutzfeldt-Jakob disease. However, our conclusion was that these cases were much different both in clinical course and in neuropathologic findings and the possibility of a new disease entity was suggested.