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June 1981

Visual Evoked Potentials in Chiasmal Gliomas in Four Adults

Author Affiliations

From the Departments of Ophthalmology (Drs Kupersmith, Siegel, and Carr and Mr. Shakin), Neurology (Dr Kupersmith), and Neurosurgery (Drs Ransohoff and Flamm), New York University Medical Center, New York.

Arch Neurol. 1981;38(6):362-365. doi:10.1001/archneur.1981.00510060064010

• Visual evoked potentials (VEPs) were recorded from four patients with surgically verified chiasmal gliomas. Despite good visual acuity, 6/12 (20/40) or better in each eye, these patients showed substantially reduced VEP amplitudes to a diffuse flash stimulus and hardly detectable responses to a highly textured checkerboard-pattern stimulus. The dissociation between evoked electrical activity and visual acuity is noteworthy; this differs from previously reported findings in patients with extrinsic compressing lesions of the chiasm or with lesions of demyelinating disease, which usually reduce VEP amplitude and increase conduction time in rough proportion to a loss of visual acuity.

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