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June 1981

Central Dazzle: A Thalamic Syndrome?

Author Affiliations

From the Department of Neurology, Boston University School of Medicine (Dr Cummings), the Departments of Ophthalmology and Neurology, Tufts University School of Medicine, Boston (Dr Gittinger), and the Boston Veterans Administration Medical Center (Drs Cummings and Gittinger). Dr Cummings is currently with the Neurobehavior Unit, Brentwood Veterans Administration Medical Center and with the Department of Neurology, UCLA, Los Angeles.

Arch Neurol. 1981;38(6):372-374. doi:10.1001/archneur.1981.00510060074014

• A patient who experienced painless intolerance to light (dazzle) three months after a right posterior cerebral artery occlusion was shown by computerized tomography to have right occipital and right thalamic infarctions. His symptoms improved with amitriptyline hydrochloride and perphenazine therapy. The sensitivity to light, delayed onset, response to therapy, and presence of a thalamic lesion are analogous to the thalamic pain syndrome and suggest that central dazzle is a variant of the thalamic syndrome.

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