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Article
June 1981

Clinical Neuroepidemiology

Author Affiliations

University of Iowa Iowa City, IA 52242

Arch Neurol. 1981;38(6):400. doi:10.1001/archneur.1981.00510060102034

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Abstract

Determining the incidence or prevalence of a disease in the community is facilitated when that condition is common, easily diagnosed, and has an easily discernible onset, persistent clinical course, and predictable outcome. Many neurologic diseases have an insidious onset, variable clinical manifestations, a remittent course, and an unpredictable natural history. Pursuing the epidemiology of many neurologic diseases is thus a special challenge that begins with the clinician, who must make valid and reliable neurologic observations. This collection of articles by prominent American and British investigators offers a selection of readings in neuroepidemiologic methods and findings. The work is divided into six major sections: general aspects, cerebrovascular disease, multiple sclerosis, pediatric neuroepidemiology, neurosurgical aspects, and miscellaneous disorders.

The general principles and methods of neuroepidemiology are first presented with chapters devoted to epidemiologic statistics and terminology, disease classification methods, the application of a geographic neurologic disease registry, and the association of HLA

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