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September 1981

Internalized Capillaries in Hypokalemic Periodic Paralysis

Arch Neurol. 1981;38(9):602. doi:10.1001/archneur.1981.00510090096021

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To the Editor.—  In the article entitled "Dominantly Inherited Pseudohypertrophic Muscular Dystrophy With Internalized Capillaries" by Hastings et al (Archives 1980;37:709-714), two families with the phenotypic appearance of benign (Becker's) muscular dystrophy, but with autosomal dominant inheritance, were reported. Examination of muscle histologic features showed, in addition to myopathic changes usually seen in Becker's dystrophy, internalized capillaries in type I fibers. We have observed this unusual histologic phenomenon inPhotomicrograph of muscle fibers, showing internalized capillaries (modified Gomori's trichrome stain, x 160). another autosomal-dominantly inherited myopathy, hypokalemic periodic paralysis.

Report of a Case.—  A 32-year-old man had a 19-year history of attacks of periodic paralysis, usually occurring on the morning after exercise or a heavy, carbohydraterich meal. Low serum potassium levels were noted during attacks (1.8 to 2.3 mEq/ L). The frequency of his attacks was significantly reduced (to one mild attack every two to four months) by use of

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