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October 1981

Neurologic Complications of Hyperthyroidism: Remission of Spastic Paraplegia, Dementia, and Optic Neuropathy

Author Affiliations

From the Department of Neurology, Academic Hospital Rotterdam-Dijkzigt, Rotterdam, the Netherlands.

Arch Neurol. 1981;38(10):669-670. doi:10.1001/archneur.1981.00510100097022

Neurologic complications of hyperthyroidism are numerous.1 The patient described here was not known to have thyroid disease and was initially observed to have a combination of spastic paraplegia, dementia, and optic neuropathy. All signs and symptoms improved dramatically within two months of the institution of carbimazole treatment. The optic neuropathy was unusual because there were no clinical or radiological signs of orbital disease.

REPORT OF A CASE  A 72-year-old man was admitted with a six-month history of a slowly progressive gait disturbance, which consisted of weakness of the legs and loss of balance. In addition, he had become confused and uninterested in his surroundings during the last two years. He could not go out alone because he easily lost his way. Both symptoms had greatly worsened during the three weeks before admission. He had become severely apathetic, could not walk, and on several occasions had been incontinent of

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