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November 1981

Dysmaturation in Infants of Mothers With Myotonic Dystrophy

Arch Neurol. 1981;38(11):716-719. doi:10.1001/archneur.1981.00510110076013

We examined the pathologic findings in four infants of mothers with myotonic dystrophy. Four of the anomalies present in these infants (nesidioblastosis, renal blastema, cryptorchidism, and patent ductus arteriosus) represent persistence of fetal organ structures or configurations. We suggest that a maturational defect may be present not only in muscle, but also in other tissues.