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Article
November 1981

Dysmaturation in Infants of Mothers With Myotonic Dystrophy

Author Affiliations

From the Departments of Neurology (Drs Young, Zalneraitis, and Krishnamoorthy) and Pathology (Dr Gang), Massachusetts General Hospital and Harvard Medical School, Boston. Dr Young is now with The Milton S. Hershey Medical Center, Pennsylvania State University, Hershey, Pa.

Arch Neurol. 1981;38(11):716-719. doi:10.1001/archneur.1981.00510110076013
Abstract

We examined the pathologic findings in four infants of mothers with myotonic dystrophy. Four of the anomalies present in these infants (nesidioblastosis, renal blastema, cryptorchidism, and patent ductus arteriosus) represent persistence of fetal organ structures or configurations. We suggest that a maturational defect may be present not only in muscle, but also in other tissues.

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