• A patient had a five-year history of sleep disturbance that culminated in a confusional illness with convulsions from which he made a partial recovery. On three separate occasions, the same ameba (Hartmannella rhysodes) was seen in and cultured from the patient's CSF. There was a rising serum titer of immobilizing antibody against the isolated strain of the ameba. The diagnosis of chronic amebic meningoencephalitis was considered in this patient.
Cleland PG, Lawande RV, Onyemelukwe G, Whittle HC. Chronic Amebic Meningoencephalitis. Arch Neurol. 1982;39(1):56–57. doi:10.1001/archneur.1982.00510130058016
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