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January 1982

Chronic Amebic Meningoencephalitis

Author Affiliations

From the Departments of Medicine (Drs Cleland, Onyemelukwe, and Whittle) and Microbiology (Dr Lawande), Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. Dr Cleland is now with the Newcastle General Hospital, Newcastle upon Tyne, England.

Arch Neurol. 1982;39(1):56-57. doi:10.1001/archneur.1982.00510130058016

• A patient had a five-year history of sleep disturbance that culminated in a confusional illness with convulsions from which he made a partial recovery. On three separate occasions, the same ameba (Hartmannella rhysodes) was seen in and cultured from the patient's CSF. There was a rising serum titer of immobilizing antibody against the isolated strain of the ameba. The diagnosis of chronic amebic meningoencephalitis was considered in this patient.

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