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February 1982

Human Rabies Transmitted by Corneal Transplant

Author Affiliations

From the Center for Infectious Diseases, Centers for Disease Control, Atlanta (Drs Baer and Gardner and Messrs Shaddock and Harrison); and the National Institutes of Health, Bethesda, Md (Dr Houff).

Arch Neurol. 1982;39(2):103-107. doi:10.1001/archneur.1982.00510140037010

• The cornea may serve as diagnostic tissue in rabies infection, with Negri bodies or fluorescing cells found in corneal epithelial cells. A recently published case history of human rabies transmission by corneal transplant focused on this rare route of infection. In the current review of postmortem findings in this case, additional data are presented that were not included in the preliminary report. These further emphasize the need to evaluate carefully all donors selected for corneal transplant.

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