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April 1982

Colpocephaly: An Error of Morphogenesis?

Arch Neurol. 1982;39(4):243-246. doi:10.1001/archneur.1982.00510160049011

• In colpocephaly, a specific form of fetal ventricular configuration persists into postnatal life. The occipital horns are disproportionately large and dilated. The condition is associated with mental retardation and is easily recognized by computed tomography or pneumoencephalography. Eight new cases of this condition are described and the pathogenesis is discussed. It is concluded that colpocephaly is an error in morphogenesis of diverse origins.