• The cytoarchitecture of the brain of a patient with developmental dyslexia was analyzed. The cortical abnormalities, consisting of micropolygyria encompassing most of posterior temporoparietal area and ectopic cell collections elsewhere have been described previously. In this study, the posterior thalamus was likewise analyzed, and a bilateral disruption of cytoarchitecture was noted in the medial geniculate nucleus and the lateralis posterior nucleus, a nuclear group of probable relevance to language found to be asymmetric.
Galaburda AM, Eidelberg D. Symmetry and Asymmetry in the Human Posterior ThalamusII. Thalamic Lesions in a Case of Developmental Dyslexia. Arch Neurol. 1982;39(6):333–336. doi:10.1001/archneur.1982.00510180011002
Customize your JAMA Network experience by selecting one or more topics from the list below.