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June 1982

Opsoclonic Cerebellopathy: Spontaneous Remission

Author Affiliations

Columbus Children's Hospital Division of Neurology Columbus, OH 43205

Arch Neurol. 1982;39(6):387. doi:10.1001/archneur.1982.00510180065027

To the Editor.—  A recent case report (Archives 1981;38:780-781) described a patient with opsoclonic cerebellopathy that apparently responded to therapy with thiamine hydrochloride. This syndrome has, in some cases, also been reported to respond to corticotropin.1-3 I observed the gradual, complete, spontaneous remission of this disease in. young child who received no therapy.

Report of a Case.—  A 2-year-old boy was admitted to the hospital shortly after the onset of ataxia. Medical and family histories were unremarkable. Results of a general examination were normal. There were no dysmorphic features, and his intelligence was appropriate for his age. The fundi were normal. The child had severe truncal and limb ataxia to such degree that he could not walk or sit without titubation. There was also obvious opsoclonus, with random, prominent, conjugate eye movements. Otherwise, his cranial nerves, reflexes, and strength were normal.The following laboratory results and levels were normal

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