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July 1982

Examination of Dental Pulp to Diagnose Infantile Neuroaxonal Dystrophy

Author Affiliations

From the Departments of Neurology (Drs Carlo, Willis, McGarry, and Duncan), Pediatrics (Drs Willis and Duncan), and Pathology (Dr McGarry), Louisiana State University Medical Center, New Orleans.

Arch Neurol. 1982;39(7):422-423. doi:10.1001/archneur.1982.00510190040012

• An 8-year-old child died after a clinical course characteristic of infantile neuroaxonal dystrophy. Typical axonal spheroids were found at autopsy and had been seen on a peripheral nerve biopsy specimen taken before death. Identical histologic abnormalities of nerve were present in dental pulp both before and after death, suggesting that histologic examination of dental pulp can aid in the antemortem diagnosis of this disorder.

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