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July 1982

CNS Infections Caused by Eikenella corrodens

Author Affiliations

From the Departments of Pediatrics (Drs Brill and Kaplan) and Neurology (Drs Brill, Pearlstein, and Mancall), Hahnemann Medical College and Hospital, Philadelphia.

Arch Neurol. 1982;39(7):431-432. doi:10.1001/archneur.1982.00510190049015

Eikenella corrodens, a slow-growing, microaerophilic, Gram-negative bacillus, was isolated from a patient with subdural empyema. Fourteen previous reports on patients with CNS infection caused by this agent, including meningitis, brain abscess, and subdural empyema, have been found. The mortality was 38%. Eikenella corrodens, found in primary infections of the ear and paranasal sinuses and in pulmonary and dental infections, is usually part of a mixed infection in which other aerobes and anaerobes, particularly Streptococcus, can be cultured. The high mortality may reflect unfamiliarity with the microbiologic characteristics of this organism and its antibiotic susceptibility.

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