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July 1982

Organic Mental Syndrome in Parkinson's Disease

Author Affiliations

Department of Neurology University Hospitals of Cleveland Cleveland, OH 44106

Arch Neurol. 1982;39(7):456-457. doi:10.1001/archneur.1982.00510190074033

To the Editor.—  I was surprised at the low incidence (15% ) of organic mental syndrome (OMS) in "typical" parkinsonism patients as described in the article "Organic Mental Syndrome and Confusional States in Parkinson's Disease" by Sroka et al (Archives 1981;38:339-342). In the study by Celesia and Wanamaker,1 40% of patients with idiopathic Parkinson's disease were found to be demented. Lieberman et al2 reported that 32% of 520 patients with Parkinson's disease had moderate to severe dementia. In the study by Boller et al,3 42% of patients with Parkinson's disease proved at autopsy had senile plaques and fibrillary tangles in the cerebral cortex. In my own small series (unpublished data, October 1978 to August 1981), I have found 45% of "typical" parkinsonism patients to have OMS.The subjects in my study included 22 patients with idiopathic Parkinson's disease ("typical" parkinsonism) and seven patients with other syndromes ("atypical" parkinsonism).