To the Editor.—
I was surprised at the low incidence (15% ) of organic mental syndrome (OMS) in "typical" parkinsonism patients as described in the article "Organic Mental Syndrome and Confusional States in Parkinson's Disease" by Sroka et al (Archives 1981;38:339-342). In the study by Celesia and Wanamaker,1 40% of patients with idiopathic Parkinson's disease were found to be demented. Lieberman et al2 reported that 32% of 520 patients with Parkinson's disease had moderate to severe dementia. In the study by Boller et al,3 42% of patients with Parkinson's disease proved at autopsy had senile plaques and fibrillary tangles in the cerebral cortex. In my own small series (unpublished data, October 1978 to August 1981), I have found 45% of "typical" parkinsonism patients to have OMS.The subjects in my study included 22 patients with idiopathic Parkinson's disease ("typical" parkinsonism) and seven patients with other syndromes ("atypical" parkinsonism).
Hershey LA. Organic Mental Syndrome in Parkinson's Disease. Arch Neurol. 1982;39(7):456–457. doi:10.1001/archneur.1982.00510190074033
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