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September 1982

Choreoathetosis in an Infant With Tuberculous Meningitis

Author Affiliations

From the Section of Pediatric Neurology, Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC.

Arch Neurol. 1982;39(9):596. doi:10.1001/archneur.1982.00510210066019

Choreoathetosis is a relatively uncommon sign of neurologic disease in infancy. Infectious diseases associated with choreoathetosis include diphtheria, various encephalitides, neurosyphilis, pertussis, Streptococcus, and typhoid fever.1 We recently treated a patient with choreoathetosis who had tuberculous meningitis.

REPORT OF A CASE  An 11-month-old male infant was admitted with choreoathetotic movements of all extremities. Two weeks before admission, he had displayed weakness of the left arm and leg and left side of the face. The left-sided weakness gradually improved, but mild weakness remained. The muscle stretch reflexes were hyperactive on the left, and the tone of the left arm and leg was increased.A chest roentgenogram showed a rightsided middle lobe infiltration. The patient's Mantoux and Candida skin tests were negative, although both were positive in the child's mother and maternal aunt.The patient's Mantoux skin test was repeated two weeks later and was then positive. Cranial computed tomography