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September 1982

Tracing Neural Connections With Horseradish Peroxidase

Author Affiliations

Department of Anatomy University of Iowa Hospitals Iowa City, IA 52242

Arch Neurol. 1982;39(9):600. doi:10.1001/archneur.1982.00510210070022

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This is a thorough state-of-the-art book dealing with the usefulness of horseradish peroxidase (HRP) as a marker for ascertaining neural connectivity. There are three contributed chapters that deal with the light microscopic, electron microscopic, and intracellular application of HRP methods. All are superb from the point of view of method and contain useful surplus information pertaining to both descriptive and dynamic aspects of neurocytology. They are well written and stress both the positive aspects and the potential pitfalls of HRP methods. In general, the book is for the specialist and student of neuroanatomy whose research interest entails coming to grips with neural connectivity. However, HRP methods in some fashion pervade many neuro-science disciplines, and all users of this marker and gift from Mother Nature will find useful information in the book.

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