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November 1982

Hypermagnesemic Periodic Paralysis: Treatment With Digitalis and Lithium Carbonate

Author Affiliations

From the Department of Neurology, University Hospital, Homburg, Saar, West Germany.

Arch Neurol. 1982;39(11):727-730. doi:10.1001/archneur.1982.00510230053017

• An 18-year-old man suffering from a hereditary hyperkalemic periodic paralysis showed, in addition, a hypermagnesemic periodic paralysis with a 2.5-fold increase in serum magnesium level. All other serum electrolyte levels were normal. The hypermagnesemic periodic paralysis seems to have been caused by a disturbance of the renal tubular system. Thus, magnesium-stimulated paralysis was prevented by treatment with lithium carbonate and digitalis, which blocked the active ion transport.